Contact Information


  • Division Secretary


    General Questions
    Phone: 404.727.7423
    Fax: 404.727.3212
    Email Us

  • Customer Service


    Billing
    Phone: 404.727.8395
    Fax: 404.727.8762
    Email Us

  • Animal Orders & Transfers
    Phone: 404.727.7426
    Fax: 404.727.8762
    Email Us

    Smartkeys Add/Modify
    Phone: 404.727.7426
    Phone: 404.727.3210
    Fax: 404.727.8762
    Email Us

  • Facility Access


    Normal Business Hours

    (Monday thru Friday, 8AM - 5PM)


    Phone: 404.727.8991

    After Normal Business Hours

    (Weekends, Holidays & After Hours: 5PM - 8AM)


    Phone: 404.727.6111

  • Animal Care & Husbandry


    Normal Business Hours

    (Monday thru Friday, 8AM - 5PM)


    Phone: 404.727.2955

  • Veterinary Medical Needs


    Normal Business Hours

    (Monday thru Friday, 8AM - 5PM)


    Phone: 404.727.3248

  • After Normal Business Hours

    (Weekends, Holidays & After Hours: 5PM - 8AM)


    Phone: 404.727.6111


Postal Mailing Address


  • 615 Michael Street
    Whitehead Biomedical Research Bldg
    Suite G-02
    Atlanta, GA 30322
    MAILSTOP: 1941-001-1AA

  • Business Hours

  • Monday - Friday
    8:00AM - 5:00PM





Emory Mouse Colony Health Surveillance and Maintenance Program



Background


Emory University has been continuously accredited by AAALAC international since 1992. Mice entering into colonies maintained at Emory University may originate from one of three sources: 1) Approved commercial vendors, 2) DAR quarantine, or 3) The Emory Transgenic Mouse Core. Mice are verified to be free from a defined set of adventitious pathogens upon entry into a colony, and policies are in place to help maintain this ‘Specific Pathogen Free’ (SPF) status. It is the primary objective of the health surveillance program to monitor colonies for the presence of agents that would compromise the SPF status so that appropriate management steps can be taken should they be found. Sentinel mice are at the heart of the surveillance program, serving as the surrogates of health status for the colonies they represent. All mouse colonies are integrated into a disease surveillance program with the exception of those housed in biocontainment areas.



Primary Mouse Housing Locations
Conventional SPF Facilities

  • Whitehead Biomedical Research Building (WBRB)
  • Rollins Research Building (RRB)
  • Woodruff Memorial Research Building (WMRB)
  • Pediatrics building (Peds)
  • B-Clinic 3rd Floor (B3)
  • B-Clinic Tunnel Level (BT)


High Level SPF Facility

  • Health Sciences Research Building (HSRB)


Mouse Sentinel Program Overview
Sentinel mice are 4-6 week old female outbred stock animals ordered from commercial vendors. 5% of the sentinel animals are isolated upon arrival, housed in sterile caging for 3 weeks and then tested to verify acceptable health status. Mice deployed to housing rooms are paired. One cage is placed per each side of a ventilated rack and one cage per whole rack for static caging. Ventilated cages are changed biweekly and static cages weekly. During cage change, dirty bedding is transferred from cages holding colony mice to another that will contain the sentinel mice. No more than 14 cages are sampled per cage change session. Dirty bedding transfer is continued for 3 months—the ‘Active Period’ and then mice are maintained on clean bedding for 6 weeks to allow for potential seroconversion—the ‘Inactive Period’. Sentinel animals are collected from their housing rooms quarterly, humanely euthanized, and samples are procured for testing. At the time of sample collection, a gross necropsy is performed. All testing except for gross dissection and physical examination for fur mites is done at commercial laboratories. Sentinels in conventional SPF housing locations are minimally tested for agents using methods and at the frequency shown in Table 1. The additional agents monitored, methods used, and frequency tested in high SPF rooms are shown in Table 2. Note that some buildings have specialized rooms that necessitate testing in addition to that shown in the tables, and health reports for those rooms will indicate any additional agents monitored. All sentinel animal test results can be viewed online at http://www.dar.emory.edu/vetcare/sentinel_mouse_results.php.





Enzootic agents
Sentinel mice in conventional housing areas are routinely positive for mouse norovirus and the agent is considered enzootic in Emory mouse colonies. No steps are taken to manage this agent.


General Husbandry Practices for Mice
Cage bottoms are changed out weekly if static microisolator and every two weeks if ventilated systems. Corn cob bedding and a nestlett is used in all strains except in nude mice, which receive Alpha-dri bedding and no nesting material. Water bottles, if present, are replaced and food is added during each cage change. Wire bar lids and food hoppers are replaced when visibly soiled or when a cage is depopulated. It is estimated that these components are sanitized once per month and every other month for rats and mice respectively.


Biological materials screening policy
All biological materials administered to rodents in Emory colonies must be screened for adventitious pathogens in accordance with DAR policy, which can be viewed at http://www.dar.emory.edu/vetcare/Cell_and_biological_testing_policy.pdf